The Polies are depressed, when Pappy left that he is all tapped out, and he has been welcome to Gloomius Maximus glum side that he'll never be happy again.
Lois Lane suffers depression when Superman dies after his intense battle with Doomsday.
Flint Lockwood depressed when his father, Tim Lockwood disowns him at the restaunt they go to.
Sunset Shimmer suffering depression as she was regretting her harsh words after briefly snapping at her friends and barking at human Twilight Sparkle for meddling with forces she doesn't understand and her friendship with her is tested.
Upin and Ipin suffering depression as they regretting their mischief actions after they made Ehsan disappears and all of their friends ostracized both of them for their disgraceful antics and their friendship with them is hurt.
Mater suffer depression after being selfishly accused by Lightning McQueen for causing him to lose the race in Japan.
Peter Parker depressed after his uncle Ben Parker is killed.
Betty Barrett suffer depression as she cries when Galactic Headquarters have been destroyed.
Flint Lockwood suffer depression after he humiliates himself at a promotion ceremony.
Arnold Shortman and Harold Berman both suffer depression after Principal Wartz suspends Arnold for two days and Harold for five weeks.
Sweet Mayham, Benny, Unikitty, Batman, and Metalbeard suffering after it's too late because of Our-Mom-Ageddon.
Osmosis Jones suffers depression after getting fired from the Frank Police Department for popping a zit without a permit by Mayor Phlegmming.
Bumblebee depressed after he saw that Optimus Prime was surrendered by countless Decepticons on Cybertron as he was launched from it.
Inspector Gadget suffers depression as he has given up being a crime fighter after getting fired from the Riverton Police Department for failing to stop Claw and ruining the science convention.
Link depressed after he finds out that he was adopted by The Great Deku Tree following his mother's death during an Hyrule Civil War.
Eddy suffering depression after his last scam
Timon suffering depression after the Hakuna Matata is gone and Pumbaa and Simba leaving.
Lincoln Loud suffering depression after he didn't have a ticket from Smooch because of his sisters.
Marge Simpson suffering depressed after discovering the tape of Homer and Bart.
Kane depressed after Lita left and dumped him for Edge.
Dave Seville depressed as he misses his boys (Alvin, Simon and Theodore) after they moved in with Ian Hawke.
Fred Flinstone depressed and heartbroken as he regrets his pompous actions as both Wilma and the Rubbles abandon him in anger, leaving their relationship tested and he realizes he's been tricked by Cliff Vandercave.
Pecos Bill depressed after seeing Slue-Foot Sue landing on the moon and will never return.
Robin gets depressed after his friends broke his bo staff
Robin gets depressed that he didn't get his own movie becuase he's being called a joke and a sidekick.
Bonnie Anderson gets depressed about having Forky and Woody missing.
Robin's depression of missing his friends
Ned Flanders gets depressed about being a single parent and realizing that he can no longer bare his single life.
Simba suffering depression when his daughter Kiara furiously tells him that he will never be his late father Mufasa, which will likely to happened, if he still refusing to reconsider his mistakes he had done to Kovu by exiling him, breaking the Circle of Life and failing to fulfill his father's goals that he himself must followed.
Lewis Robinson Feels Depress when Wilbur Didn't Promise him.
Link and Princess Zelda's depression over losing everything and everyone they loved because of Calamity Ganon's return.